| Specifications | |
|---|---|
| Sensitivity | 1.0 ng/mL |
| Assay Type | ELISA |
| Pack size | 1×96 wells |
| Species Reactivity | Human |
| Antibody Type | IgG |
| Contents | Microtiter plate Enzyme conjugate Standard A Standard B Standard C Standard D Standard E Standard F Substrate A Substrate B Stop solution Wash solution Balance solution |
| Sample Requirement | Plasma, Serum |
| Storage | Short term: 4°C, Long term: See manual. |
| Target Information | |
|---|---|
| Target | Angiotensin 2 Receptor 1 autoantibody |
| Alternative Names | Angiotensin II Receptor Type 1 autoantibody; AT2R1 autoantibody; AT1 autoantibody; AGTR1A autoantibody; AT2R1B autoantibody; AGTR1B autoantibody; HAT1R autoantibody; AG2S autoantibody; AT1B autoantibody; Type-1 Angiotensin II Receptor autoantibody; AT2R1A autoantibody; AT1AR autoantibody; AT1BR autoantibody; Type-1B Angiotensin II Receptor autoantibody; Angiotensin II Type-1 Receptor autoantibody; Angiotensin Receptor 1B autoantibody; AT1R autoantibody |
| Introduction | Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Alternative splicing of this gene results in multiple transcript variants. |