Cyclosporin A Mouse Monoclonal Antibody [Clone ID: 4A3 (CSZ.22)] - 200 ug

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    Clone Name4A3 (CSZ.22)
    ApplicationsELISA
    Recommended DilutionELISA.
    HostMouse
    IsotypeIgG1
    ClonalityMonoclonal
    ImmunogenCyclosporin A conjugated to an HMW carrier
    SpecificityThis antibody recognizes Cyclosporin A, a widely-used immunosuppressant drug from the fungus Tolypocladium inflatum.
    FormulationPBS
    State: Purified
    State: Liquid (0.45 µm filtered) purified IgG fraction
    Preservative: 0.09% Sodium Azide
    Concentrationlot specific
    PurificationAffinity Chromatography on Protein G
    ConjugationUnconjugated
    StorageStore undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
    Avoid repeated freezing and thawing.
    StabilityShelf life: one year from despatch.
    BackgroundCyclosporin is used to prevent rejection following solid organ and bone marrow transplantation . It has been estimated that cyclosporine is given to more than 90% of children who have received a kidney transplant in the United States. In addition, the ability of cyclosporin to inhibit T-cell activation has been shown to have a role in the treatment of diseases such as nephrotic syndrome, refractory Crohn's disease and ulcerative colitis, biliary cirrhosis, aplastic anemia, rheumatoid arthritis, myasthenia gravis, and dermatomyositis.